What is PQQ?


Never heard of Pyrroloquinoline Quinone (PQQ)? You’re not alone.

PQQ is a multi-functional nutrient with uniquely powerful benefits and yet remains one of the best kept secrets in the nutritional supplements community. Select a question from our FAQ guide to learn more about what makes PQQ an emerging superstar of supplements.

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Frequently Asked Questions about PQQ

What is PQQ?

PQQ (Pyrroloquinoline Quinone) is a leading edge supplement that offers remarkable benefits for a versatile range of uses. This vitamin-like micronutrient can be found everywhere in nature — soil, plants, fruits, and animals.  It is essential for a healthy mind, heart and body.

What are the benefits of PQQ?

Among its wide range of benefits, PQQ is commonly used as anti-aging prevention and protection for the health of your most vital organs, including the brain, heart, and liver. Studies have shown that PQQ can provide:

Neurological support:

PQQ enhances cognitive function and improves short-term memory. It can help the brain to prevent memory loss and cognitive decline due to age and neurodegenerative disorders. With its ability to restore damaged brain and nerve cells, it has also been shown to promote recovery in cases of stroke and cerebral infarction.

Cardiovascular support:

PQQ improves blood circulation and cardiac function, supporting energy production in the heart and providing powerful antioxidant protection.  Studies indicate that PQQ can also promote recovery from heart attacks and reduction of infarct size.

Liver support:

PQQ aids the liver with fat metabolism to break down more fats and convert into greater energy output. Clinical results show it may also reverse acute and chronic liver injury, including damage from fatty liver disease.

In addition to supporting your vital organs, PQQ is used as regular supplementation to augment and sustain higher levels of natural energy production. By stimulating your body’s pure energy production at the cellular level, PQQ serves as an excellent energy supplement for a broad range of uses. It is especially ideal as a sports and fitness supplement for athletes seeking more pure and natural alternatives to boost their performance.

Perhaps the most unique and unexpected benefit of PQQ is its use for cosmetic and skincare applications. It rejuvenates your skin cells, rebuilding healthy tissue for thicker skin and fewer wrinkles. PQQ can be effective as anti-aging prevention not just for your brain, heart and liver, but also as a cosmetic anti-aging treatment for your skin.

In short, PQQ is the emerging superstar supplement with a variety of benefits to revitalize your mind and body.

How does it work?

The wide array of PQQ’s benefits are all derived from three primary functions that it provides

New Mitochondrial Growth:

Mitochondria are the powerhouses of the cell and produce the vast majority of all cellular energy (ATP). PQQ activates a key transcription factor protein (CREB) and directly stimulates Mitochondrial Biogenesis, which is the growth and replication of new mitochondria. Stronger mitochondria, and more of them, produce more cellular ATP and thereby, users of PQQ may feel higher levels of natural energy.

Powerful Antioxidant:

Antioxidants protect your cells from damage inflicted by harmful molecules called free radicals. PQQ is an extremely potent antioxidant and is approximately 100 times more effective than Vitamin C at reducing these free radicals. A continuous supply of PQQ provides long-lasting protection and promotes the longevity of your heart, brain, liver and other organs rich in mitochondria.

Nerve Cells Support:

Nerve Growth Factor (NGF) is a small protein that plays a critical role in the growth, development and maintenance of neurons. PQQ has been found to promote NGF production, with one study showing as much as a 40x increase. Increased levels of NGF help to maintain the health of the brain and peripheral nerves while also stimulating nerve regeneration. This promotes more mental energy, greater focus, and better short-term memory.

As a powerful antioxidant, a stimulator of mitochondrial biogenesis and a trigger of Nerve Growth Factor production, PQQ is a triple threat to cellular aging.

Should I take both CoQ10 and PQQ?  

CoQ10 is a popular and widely consumed supplement for mitochondrial health. Its benefits include facilitating more efficient production of ATP cellular energy, providing a “spark” for generating energy inside your mitochondria. PQQ is an ideal complement to CoQ10 because PQQ stimulates the growth and replication of those same mitochondria. More mitochondria with more spark means even more energy. If you’re already taking CoQ10, taking PQQ in addition can have a multiplier effect in enhancing the benefits of CoQ10 and work in concert to maximize your boost in pure and natural energy.

PQQ and CoQ10 can be purchased and taken separately. Additionally, they are often sold formulated in combination, such as this product from Doctor’s Best featuring PureQQ®.

Where can I get PQQ?

Foods that are rich in PQQ include celery, parsley, kiwi, papaya, spinach, beans, potatoes and fermented bean products. It is also naturally found in breast milk, an excellent source of PQQ that infants can benefit from.

In addition to a natural diet consisting of PQQ-rich foods, dietary supplements are a convenient way to ensure a recommended daily intake of this essential nutrient. PQQ supplements are widely available at retail locations as well as online retailers including Vitamin Shoppe, Swanson Vitamins, Walgreens, Amazon, GNC, Walmart and many more. Look for the PureQQ® logo to ensure you have the highest quality PQQ product possible.

How much PQQ should I be taking?

PQQ supplements are most commonly sold at 10mg, 20mg and 40mg. For new users of such supplements, it is recommended to start at a dosage of 10-20mg per day. Monitor the effects and adjust the dosage accordingly over time.

Are there any side effects?

Wide-ranging studies have been conducted to test the safety and side effects of PQQ. In one study, 20mg of PQQ taken over a course of 12 weeks was shown to cause no toxicity or adverse symptoms. Other studies over different testing periods have also concluded that PQQ consumption at 20mg per day is perfectly safe for adults.